2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-DY1062
    Cy5.5 (solution) 210892-23-2
    Cy5.5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Solution Concentration: 10 mM
    Cy5.5 (solution)
  • HY-E70252
    1-Pyrenebutanoyl-CoA 81923-89-9 98%
    1-Pyrenebutanoyl-CoA is a type of coenzyme A that can non-competitively inhibit (Ki = 2 μM) phosphorylating (ADP-stimulated) respiration in rat liver mitochondria, and competitively inhibit (Ki = 2.1 μM and 15 μM) carnitine palmitoyl-CoA transferase and octanoyl-CoA transferase.
    1-Pyrenebutanoyl-CoA
  • HY-E70292
    N-Acetylgalactosaminyltransferase 11 98%
    N-Acetylgalactosaminyltransferase 11 (GALNT11) is a glycosylation transferase capable of activating the Notch signal.
    N-Acetylgalactosaminyltransferase 11
  • HY-E70389
    Human Kallikrein 98%
    Human Kallikrein is a serine protease that can be found in plasma and tissue. Human Kallikrein has the potential for the research of blood pressure, complement activation, and mediation and maintenance of inflammatory responses.
    Human Kallikrein
  • HY-E70390
    C1s Enzyme
    C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity.
    C1s Enzyme
  • HY-E70413
    Amino acid arylamidase, hog kidney 9012-21-9 98%
    Amino acid arylamidase, hog kidney is a metalloprotease that can hydrolyze proteins or peptides containing free α-amino or α-imino groups, playing a crucial role in amino acid metabolism and protein digestion. Its hydrolytic activity can be blocked by acetylation of the N-terminus. Amino acid arylamidase, hog kidney can be used in research on hepatic diseases, biliary diseases, and heart failure.
    Amino acid arylamidase, hog kidney
  • HY-E70542
    Bovine Factor V/Va 98%
    Bovine Factor V/Va can be purified from fresh bovine plasma and used as a source of V/Va in the prothrombinase complex.
    Bovine Factor V/Va
  • HY-E70559
    Prostaglandin D synthase 65802-85-9 98%
    Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type Prostaglandin D synthase (L-PGDS) is present in the atherosclerotic plaque of the human coronary artery and can be detectable in human serum.
    Prostaglandin D synthase
  • HY-E70782
    TIE2 R849W Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 R849W is the most common mutation implicated in an inherited form of vascular malformations. TIE2 R849W Recombinant Human Active Protein Kinase is a recombinant TIE2 R849W protein that can be used to study TIE2 R849W-related functions.
    TIE2 R849W Recombinant Human Active Protein Kinase
  • HY-E70783
    TIE2 Y1108F Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y1108F is the most mutation of TIE2. TIE2 Y1108F Recombinant Human Active Protein Kinase is a recombinant TIE2 Y1108F protein that can be used to study TIE2 Y1108F-related functions.
    TIE2 Y1108F Recombinant Human Active Protein Kinase
  • HY-E70784
    TIE2 Y897S Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y897S is the most mutation of TIE2. TIE2 Y897S Recombinant Human Active Protein Kinase is a recombinant TIE2 Y897S protein that can be used to study TIE2 Y897S-related functions.
    TIE2 Y897S Recombinant Human Active Protein Kinase
  • HY-E70797
    Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. One member, CAMK2δ CAMK2D is involved in vasopressin signaling in the renal collecting duct, which controls water excretion through regulation of the water channel aquaporin-2 (AQP2). Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase is obtained by expressing CaMK2δ CAMK2D proteins and is biotinylated.
    Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase
  • HY-E70810
    CaMK1β Recombinant Human Active Protein Kinase
    CaMK1 is present in several cell types and may be involved in various cellular processes. CaMK1 exists as different isoforms (α, β, γ and δ). CaMK1β Recombinant Human Active Protein Kinase is obtained by expressing CaMK1β proteins.
    CaMK1β Recombinant Human Active Protein Kinase
  • HY-E70811
    CaMK2α Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. CaMK2α Recombinant Human Active Protein Kinase is obtained by expressing CaMK2α proteins.
    CaMK2α Recombinant Human Active Protein Kinase
  • HY-E70812
    CaMK2β Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. CaMK2β Recombinant Human Active Protein Kinase is obtained by expressing CaMK2β proteins.
    CaMK2β Recombinant Human Active Protein Kinase
  • HY-E70854
    PKCε Recombinant Human Active Protein Kinase
    PKCε is an isoform of the large PKC family of protein kinases. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε modulates cardiac cell metabolism through its actions at mitochondria. PKCε Recombinant Human Active Protein Kinase is a recombinant PKCε protein that can be used to study PKCε-related functions.
    PKCε Recombinant Human Active Protein Kinase
  • HY-I0400S
    N-Acetylneuraminic acid-13C 64162-77-2 98%
    N-Acetylneuraminic acid-13C is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-13C
  • HY-N0013R
    Vitexin (Standard) 3681-93-4 98.21%
    Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects.
    Vitexin (Standard)
  • HY-N0043R
    Ginsenoside Rd (Standard) 52705-93-8
    Ginsenoside Rd (Standard) is the analytical standard of Ginsenoside Rd. This product is intended for research and analytical applications. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
    Ginsenoside Rd (Standard)
  • HY-N0054R
    Osthole (Standard) 484-12-8
    Osthole (Standard) is the analytical standard of Osthole. This product is intended for research and analytical applications. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.
    Osthole (Standard)
Cat. No. Product Name / Synonyms Application Reactivity